Acupuncture for Chronic Pain: Why Treating the Nervous System Changes Everything
- Dr. Melissa Levy
- 3 days ago
- 5 min read

Chronic pain affects millions of people and remains one of the most complex and frustrating conditions to treat. Many patients are told that their pain is due to degeneration, old injuries, poor posture, or irreversible structural damage. Others are left confused when imaging looks “normal,” or when pain persists long after surgery, physical therapy, or injections.
At Integrative Wellness Center of Jacksonville, we approach chronic pain differently. We understand that persistent pain is not simply a tissue problem, it is a nervous system condition. Acupuncture, when practiced through a modern, neuroscience-informed, and integrative lens, is one of the most effective tools we have for calming the pain system and retraining the brain.
We specialize in chronic neck pain, back pain, migraines, headaches, and chronic gastrointestinal pain, using an approach that blends acupuncture, pain neuroscience education, mind-body therapy, and functional medicine.
Why Chronic Pain Persists Long After the Body Heals
One of the most important shifts in modern pain science is the recognition that chronic pain is fundamentally different from acute pain. Acute pain serves a protective purpose it alerts us to injury or danger. Chronic pain, however, often continues long after tissues have healed.
Research has shown that chronic pain is driven by changes in how the brain and spinal cord process pain signals. This process, known as central sensitization, occurs when the nervous system becomes overly responsive and begins amplifying pain signals even in the absence of ongoing injury. Over time, the threshold for pain becomes lower, non-threatening sensations can feel painful, and the body remains in a constant state of protection.
This phenomenon is closely related to the wind-up effect, where repeated pain signals sensitize the nervous system, leading to long-term changes in neural pathways. Once these pathways are established, the brain can continue producing pain even after surgeries, injections, or structural corrections. This is why so many people feel discouraged after being told everything “looks fine” on imaging, yet their pain remains very real.
Pain researchers have gone so far as to describe chronic pain as a disease of the brain, involving functional and structural changes in regions associated with threat detection, emotion, memory, and sensory processing. In other words, pain is not imagined — but it is learned and reinforced by the nervous system.
The Brain’s Role in Pain Perception
Pain does not live in the muscles, joints, or discs. Pain is an output of the brain, based on how safe or threatened the nervous system perceives the body to be. When the nervous system is chronically activated often due to stress, trauma, illness, inflammation, or repeated injury the brain becomes hypervigilant.
In this state, the nervous system prioritizes protection over healing. Muscles tighten, digestion slows, sleep becomes disrupted, and pain inhibition pathways weaken. This is why chronic pain so often overlaps with migraines, headaches, digestive disorders like IBS, anxiety, fatigue, and poor sleep.
To truly resolve chronic pain, treatment must focus on regulating the nervous system, not just correcting the body mechanically.
How Acupuncture Treats Chronic Pain at the Nervous System Level
Acupuncture has been extensively studied for chronic pain, and high-quality research consistently shows that it is more effective than sham treatments or usual care for conditions such as chronic low back pain, neck pain, osteoarthritis, and headaches. Large meta-analyses published in major medical journals have confirmed that acupuncture produces real, lasting pain relief.
From a neurological perspective, acupuncture works by stimulating sensory nerve fibers that communicate directly with the spinal cord and brain. These signals influence pain-processing centers in the brain, including the limbic system and default mode network, which are involved in emotional pain, threat perception, and memory.
Functional MRI studies demonstrate that acupuncture can calm overactive pain circuits, regulate emotional processing centers, and shift the nervous system out of chronic fight-or-flight mode. It also promotes the release of endorphins, serotonin, and dopamine, while reducing inflammatory signaling and stress hormones like cortisol.
Over time, these effects allow the nervous system to desensitize, meaning the brain no longer interprets normal input as dangerous. This is not just symptom suppression — it is nervous system retraining.
Neuroplasticity: Rewiring the Pain Pathways
Neuroplasticity refers to the brain’s ability to change and adapt. In chronic pain, neuroplasticity works against the patient, reinforcing pain pathways through repetition and fear-based learning. However, neuroplasticity can also be harnessed for healing.
Acupuncture provides repeated, safe sensory input to the nervous system. With consistent treatment, the brain begins to reinterpret signals as non-threatening. Pain pathways weaken, protective muscle guarding decreases, and the nervous system becomes more flexible and resilient.
This is why acupuncture is particularly effective for pain that has lingered for months or years, even when structural interventions have failed. It addresses the underlying neural patterns that keep pain alive.
A Fully Integrated Mind-Body Pain Approach
At our clinic, chronic pain care extends far beyond acupuncture alone. Both Dr. Doug Suffield and Dr. Melissa Levy Ellis are trained in pain neuroscience, Pain Reprocessing Therapy, and mind-body approaches to chronic pain. We understand that pain is influenced by the brain, emotions, stress physiology, immune function, and metabolic health.
This allows us to treat pain from every angle addressing not only the nervous system, but also inflammation, nutrient deficiencies, hormonal imbalances, and gut-brain contributors that can perpetuate pain sensitivity.
Our chronic pain sessions may include acupuncture combined with infrared and red light therapy, PEMF/BEMER therapy, manual therapies such as cupping and gua sha, and nervous system regulation strategies. We also provide individualized lifestyle guidance to support sleep, stress resilience, movement confidence, and recovery.
For many patients, we recommend functional lab testing to look deeper at systemic contributors to pain. Chronic inflammation, blood sugar dysregulation, nutrient depletion, and gut dysfunction can all sensitize the nervous system and must be addressed for lasting results.
What to Expect From Chronic Pain Treatment
Because chronic pain develops over time, it requires consistency to resolve. Most chronic pain cases require between twelve and twenty-four treatments, with many patients noticing improvement within the first few sessions. We typically begin with a recommendation of six to twelve treatments and reassess based on progress.
The goal is not temporary relief, but long-term nervous system change. Each session builds on the last, gradually retraining the brain and body to move out of protection and into healing.
Why Acupuncture Should Be a Priority for Chronic Pain
If you are dealing with chronic neck pain, back pain, migraines, headaches, or ongoing pain that has not responded to conventional care, acupuncture should not be a last resort. When practiced through a modern, neuroscience-informed, and integrative approach, it is one of the most powerful tools available for resolving chronic pain safely and effectively.
Chronic pain is not “all in your head,” but the brain and nervous system are central to healing it.
If you are located in Jacksonville and looking for a comprehensive, evidence-based approach to chronic pain, our clinic specializes in helping patients finally break free from the pain cycle and reclaim their quality of life.
Book your appt today!
Image credit: Credit: Northwestern University Credit: Phys.org (http://phys.org/news121498448.html)
